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Its size and complexity will allow systematic research into the genetics of many complex disorders in admixed populations and thus, by serving a wide variety of disciplines, will feed research in this promising area for many years to come.
While noncoding genetic variation has been shown to play a major role in many complex disorders, the contribution of these regions to ASD susceptibility remains unclear.
Rational design of multi-targeted drug combinations is a promising strategy to tackle the drug resistance problem for many complex disorders.
Thus, the question arose in many complex disorders if associations with previous candidate genes represent false positive results.
For addictions, as for many complex disorders, such data provides an increasingly rich basis for improved understanding and for personalized prevention and treatment strategies.
Like many complex disorders, it is unlikely that a single genetic polymorphism will explain all susceptibility to accelerated renal function decline.
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Moreover, as with many other complex disorders, AR is thought to be the result of a complicated network of numerous susceptibility loci, many of which exert additive or synergistic effects, but have only a small role when considered in isolation [31], [32].
Some of the most significant discoveries in the field of psychiatry have been made at McLean, shedding new light on the causes of and treatments for many complex neuropsychiatric disorders.
Gene-gene interactions are likely involved in many complex genetic disorders and new statistical approaches for detecting such interactions are needed.
We concluded that the CTD had adequate coverage for many common, complex disorders.
Therefore, next generation sequencing methods for gene expression profiling will change the approaches to studying many common complex disorders, including CVDs [ 53].
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