Sentence examples for many comparative genomics from inspiring English sources
Many comparative genomics projects have focused on sequencing of the genome or expressed sequenced tags (ESTs), and full-length cDNA sequences are uniquely informative resources for accurately predicting the full structure of transcripts in the genome [ 15].
In fact, many comparative genomics projects are first initiated by a simple BLAST search.
On the other hand, some other databases such as PLAZA 3.0 and EnsemblPlants are able to provide many comparative genomics tools (e.g., collinear region plot and localization plot) that PlantOrDB currently does not offer.
We demonstrate that this effect complicates the inference of constraint in the maximum-likelihood (ML) branch-length analysis that underlies many comparative genomics approaches such as GERP (Cooper et al. 2005) and PhyloP (Pollard et al. 2010).
In many comparative genomics studies, large-scale detection of tandem duplicated genes is a necessary step to tackle basic questions about gene duplication, notably the mechanisms of TGA formation and evolution.
There are many visual comparative genomics tools available, each with different advantages and disadvantages.
Many previous comparative genomics studies have found that most genes in the noncore portion of a bacterial pangenome are rare (reviewed in Gogarten and Townsend 2005; Touchon et al. 2009).
This characterization will take many approaches, including comparative genomics between the cereals and within Oryza, and utilization of the wild Oryza gene pool.
To our knowledge, this issue has not been studied in detail, despite its potential importance in many applications in comparative genomics, including phylogenetic modeling, the detection of positive selection, and comparative gene finding.
The accurate identification of orthologs and paralogs is a prerequisite for many analyses in comparative genomics and an active area of research (Dessimoz et al. 2012).
Many other computational comparative genomics methods related to gene rearrangement are also limited by the requirement that the species being compared must be closely related [ 5, 34].
