Sentence examples for many clinical isolates from inspiring English sources

Many clinical isolates have also proven refractory to the introduction of currently available shuttle vectors via electroporation.

Recent studies suggest that many clinical isolates form polysaccharide-independent biofilms.

Many clinical isolates of the human pathogen Neisseria gonorrhoeae contain conjugative plasmids.

Soon after the discovery of the EAEC pathovar it was noted that many clinical isolates of EAEC displayed multiple antibiotic resistance [27].

RC-101 inhibited the formation of HIV-1 proviral DNA [3], [7], and exhibited broad activity against many clinical isolates of HIV-1 from all major subtypes [8], [9].

Furthermore, therapy is complicated by antibiotic resistance in many clinical isolates, resulting in frequent relapse of patients and the mortality rate of patients with septic shock is approximately 80 95% despite treatment with ceftazideme, imipenem or meropenem [2].

Many B. fragilis clinical isolates are resistant to aminoglycosides, β-lactams and macrolide antibiotics [ 11].

In many azole resistant clinical isolates of C. albicans the PDR16 gene was overexpressed in addition to multidrug transporters [4].

Many of the clinical isolates of this organism carry chromosomal and plasmid-encoded genetic determinants specifying resistance to a wide range of antibiotics (Mahlen 2011) including extended-spectrum beta-lactamase (ESBL) or metallo beta-lactamase (MBL).

However, countering this is the fact that genotypic analysis for many of our clinical isolates was based on PCR analysis rather than sequencing and additional micro-mutations may have gone undetected.

Furthermore, to design therapeutic antibodies for human diseases, it is important that the selected MAbs react not only to the particular strain of bacteria used as the immunogen, but to as many different strains and clinical isolates of these two closely related species of bacterial pathogens as possible [14], [15].