Sentence examples for many chromosomal rearrangements from inspiring English sources

The genome of the derived species, pertussis and parapertussis, has a smaller size than their ancestor with a considerable increase in the number of IS elements, pseudogenes and many chromosomal rearrangements more particularly for B. pertussis.

Many chromosomal rearrangements are detected each year in France on young boars candidates for reproduction.

At the cellular level, WS fibroblasts derived from patients exhibit genomic instability demonstrated by many chromosomal rearrangements, recombination defects, and accumulation of oxidative damage [ 2- 6].

In many chromosomal rearrangements, the DSBs at one or both genes appear to be located randomly within large regions of many kilobases.

To date, many chromosomal rearrangements leading to enhanced ALK activity have been described and are implicated in a number of cancer types.

In addition, the diploid karyotypes of Microtus voles are quite variable and range from 2n = 17-64 [ 8], suggesting that many chromosomal rearrangements have been fixed in a very short amount of time.

In the rest of the syntenic groups, the gene order was not conserved, suggesting many chromosomal rearrangement events.

Many visible chromosomal rearrangements occur de novo.

Comparative analyses using such a combined approach may reveal many more chromosomal rearrangements and novel synteny groups.

Whereas solid tumors usually display complex karyotypes with many different types of chromosomal rearrangements, many hematological malignancies and certain sarcomas display only one or a few aberrations, usually balanced chromosomal translocations, which in some cases have been shown to be the initiating event in tumor development [1], [2].

Since many observed chromosomal rearrangement associated diseases are somatic cancers, which are mainly caused by mitotic recombination, it indicates that meiotic recombination may be safe but hotspot sequences may be susceptible to diseases.