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C. elegans has proven to be an excellent model for the study of many central processes in biology, including energy metabolism (Jones & Ashrafi, 2009), immunity (Schulenburg et al, 2004) and aging (Kenyon, 2010).
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For example, many central cognitive processes, such as those concerning space and time, were, claimed Lakoff and Johnson, both expressed and influenced by metaphor (hence "metaphors we live by").
Adenine dinucleotides play important roles in many central biological processes, including DNA repair [ 2, 3], glycolysis, photosynthesis, and transcription [ 4– 7].
Fatty acids also inhibit many central metabolic processes, but this may occur indirectly via uncoupling of ATP synthesis (12, 13).
The transforming growth factor-beta1 (TGF-β1) signaling pathway is a fundamental pathway in the living cell, which plays a role in many central cellular processes.
Light is an essential abiotic factor, not only because cyanobacteria obtain their entire energy through photosynthesis, but also for the activation and regulation of many central metabolic processes.
The TGF-β signaling pathway is a fundamental pathway in the living cell, which plays a key role in many central cellular processes.
About half of the diatom genes encodes for proteins of unknown function, suggesting that many regulators of central processes in diatom biology remain to be identified.
Thus many of the central processes carried out, at least in part, by nucleoli exist in all eukaryotes considered and, compared to non-nucleolar proteins, a much higher proportion of nucleolar-associated proteins are conserved amongst eukaryotic organisms.
Taken together, depending on the type of stressor, various signals converge to orchestrate an integrated stress response that 'resets' many peripheral and central processes and allow an individual to adapt to the changes in its environment and thus to restore homeostasis.
In plants, bZIPs are regulators of many central developmental and physiological processes including photomorphogenesis, leaf and seed formation, energy homeostasis, and abiotic and biotic stress responses.
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