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PKC isozymes are becoming attractive targets for therapeutic intervention because of their many cellular roles [ 64, 65].
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GSH serves many important cellular roles as a redox regulator, cofactor, substrate, and antioxidant.
Tenascin-C (TNC) is associated with cellular injury and inflammation, and has many cellular functions, with roles in embryogenesis, wound healing and cancer progression (Imanaka-Yoshida et al., 2004).
To date, one of the difficulties in separating many of the discrete cellular roles of VHL is that individual mutations in the gene result in widespread changes to the protein's function [4] [6].
For instance, although signaling molecules such as 'kinases' are known to be important in many cellular processes, some play roles in downstream signaling events associated with ROS.
As a transcription factor, many of the functional cellular roles of the p53 protein are elicited through direct DNA binding to sequence-specific cis-regulatory elements [ 3] leading to the transactivation or transrepression of target genes.
Heat shock proteins are thus believed to play a broad role in many cellular processes, which may impart a generalized role in tolerance to multiple environmental stress treatments apart from heat stress.
Nonetheless, based on its many cellular functions, the potential role of DBC1 in the regulation of metabolism, aging and tumour biology is of great importance and needs to be further explored.
Encyclopædia Britannica, Inc. Receptors play key roles in many cellular processes.
Glutathione (GSH) serves many cellular functions and plays crucial roles in human pathologies.
Phospholipid membranes and proteins embedded in them are universal components of cells and play key roles in many cellular functions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com