Sentence examples for many cell signalling from inspiring English sources

MCL1 is an early-response gene, expressed during critical transitions in cell phenotype that can be rapidly induced and repressed [47] in contribution of many cell signalling pathways like JNK/STAT3, PIK3/AKT or NFκB [48].

This behaviour is interesting because many cell signalling molecules shuttle between the nucleus and the cytoplasm.

Notably, physiological levels of ROS are required for many cell signalling events.

PIK3CA encodes the p110 catalytic subunit of phosphatidylinositol-3′-kinase, a critical component of many cell signalling pathways including those of EGF and PDGF (Volinia et al, 1994).

The coupling of pathways and processes through shared components is being increasingly recognised as a common theme which occurs in many cell signalling contexts, in which it plays highly non-trivial roles.

Curcumin is one such agent that inhibits the proliferation and angiogenesis of a wide variety of tumor cells, through the modulation of many cell signalling pathways.

For example, the membrane protein caveolin-1 has been implicated in many cell signaling pathways and diseases, yet the full-length protein is too aggregation-prone for detailed mutagenesis, directed evolution, and biophysical characterization.

Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks' output.

But proteomics presents much greater complexity than, say genomics, which many cell signaling scientists grew up learning.

PT, which is produced exclusively by B. pertussis, is a six-subunit exotoxin of AB5 configuration that ADP-ribosylates the α subunit of Gi proteins in mammalian cells, thereby inhibiting many cell signaling events through G protein-coupled receptors.

The simple and robust procedure elaborated here to assemble multilayered biomimetic structures will be instrumental to reconstitute multimolecular complexes involving both cytosolic and membrane embedded proteins such as those implicated in many cell signaling pathways and will also be useful to characterize protein translocation across membranes.