First, these pathways are frequently activated in human cancer, thus in many cases, targeting the cascades will suppress cell growth, in the absence of knowing the precise mutation(s) responsible for the cancer.
In many cases these targets are not only considered as imaging targets, but also as targets for treatment [ 70– 72].
Although the majority of miRNA candidates seem to have more than two targets, detailed analysis reveals that in many cases the targets annotated with different UniRefs have the same gene description (Additional file 2: Table S7).
These targets included transcripts encoding proteins involved in enzymatic activity and structural proteins although in many cases the targets were identified as unknown proteins or not annotated.
The CEERES project has suggested two main causes for this: In many cases the targets have not been set on a basis of any thorough analysis and the support systems have not been designed adequately.
Further, in many cases the targets of activity-based probes are already known (Simon et al, 2013), so this would also yield protein identification in one experiment.
6 The DUTY register in Germany shows that, in many cases, the targets for cardiovascular risk factors are not achieved by patients with T2DM.
In many cases such target identification is unable to identify one or more target.
The target may be a peptide, or a glucide, or a lipid; in many cases, the target is a protein [10, 11].
In many cases, the target of a national security letter whose records are being sought is not necessarily the actual subject of a terrorism investigation and may not be suspected at all.
In many cases, the target for revenge becomes broader and more symbolic than a single person, so that an entire type or category of people is deemed responsible for the attacker's pain and suffering.
