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This new view will include many biological modules that can not be revealed by finding densely connected regions such as cliques or k-cores.
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Hub proteins have many connections, may be involved in various biological modules and play a central role in all biological processes.
As a result, genes in the module significantly involved in many biological pathways such as "NOD-like receptor signaling pathway", "MAPK signaling pathway", "apoptosis," and "tight junction" that have been known as hallmark processes of tumor).
It is known that many biological pathways do not necessarily form densely connected modules.
MAPK signal transduction modules play crucial roles in regulating many biological processes in plants, which are composed of three classes of hierarchically organized protein kinases, namely MAPKKKs, MAPKKs, and MAPKs.
MAPK signal transduction modules played important roles in regulating many biological processes in plants [ 39].
The flexibility given by the possibility of running many different analysis modules in parallel is of particular interest, as in many biological case studies the searched pattern in experimental results is unknown and might require to try different kinds of analysis since modules can be swept in parallel.
Many biological entities, from brains to gene regulatory networks, are organized into modules – dense clusters of interconnected parts within a complex network.
Characterizing the interactions of these peptide recognition modules will help us map and understand the many biological processes they mediate.
Since many biological functions are naturally regulated using a similar principle, synthetic protein sensing modules can be created by joining these individual protein domains into a cooperative input output mechanism.
In many studies such enriched communities are found, and hence are plausible candidates for biological modules.
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