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Many biological changes have been observed among different trophic levels of the North Sea from phytoplankton to fish, as the North Sea has warmed [ 1].
Rather than caused by a single 'malignant' pathway, RV failure is the resultant of many biological changes, both adaptive and maladaptive.
Already in the 80s, Bortz [ 12] indicated that many biological changes that are commonly attributed to ageing, e.g. sarcopenia, can be reverted, since they are mostly caused by disuse.
Existing evidence suggests that a higher prognostic value is associated not with a single marker but with a combination of them; inflammation-based scores reflect many biological changes connected with cancer, and the impact of systemic inflammation on various aspects of patient's physiology [ 86, 87].
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These values are not optimal for elderly patients, as many biological markers change over time and adequate reference intervals are important for correct clinical decisions.
Lastly, ICE-FIRST gave us our first glimpse at the genomic response to spaceflight, suggesting that altered Insulin and/or TGF-beta signaling in flight may underlie many of the biological changes seen in response to spaceflight.
Social priorities develop and many biological and physiological changes occur during this time, 7 and often adolescent physical activity promotion interventions specifically target girls 57 58 to address some of these issues.
The four single color PRIGs are therefore also suitable for performing double or even triple transductions, which may be required in many situations to induce biological changes [ 17].
Thus, the difficulties imposed by the birth process and the passage of the head and shoulders through the bony pelvis seem to have driven biological changes in many aspects of pregnancy.
Recent microarray analyses of anurans and salamanders show that amphibian metamorphosis involves thousands of gene expression changes, involving many biological processes that have previously received little attention [ 9, 10].
Although caloric restriction has produced dramatic changes in many biological systems and proven beneficial to obese adults suffering from knee OA, no study has directly addressed whether intensive dietary induced weight loss also slows the progression of structural damage in people with OA or determined mechanistically how it happens.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com