As already discussed, plasma contains many bioactive substances, such as cytokines, immunoglobulin, and coagulation factors.
For many bioactive substances (lutein, lycopene, coenzyme Q10) and some essential nutrients (vitamin B12 and the amino acids), no hazard has been identified and thus no NOAEL.
The carob fruit, brown pod 10 25 cm in length, contain many bioactive substances such as sweet carbohydrate, dietary fiber, tannins, and polyphenols [ 11].
As plasma contains many bioactive substances, such as cytokines, it has been presumed that it could induce notable changes in the patient's immunity status.
Abdominal obesity, especially a visceral fat, may play a key role in these situations, because adipose tissue is known to secrete many bioactive substances, including inflammatory and anti-inflammatory proteins [ 11, 12].
Modern biotechnology has greatly increased our knowledge about the gene sequences and receptors of many bioactive substances and although artificially synthesized growth factors are more costly with short half-lives, they are convenient and their application is not restrained by the physical condition of the patient.
It is known that the submandibular gland (SMG) of the male mouse contains many important bioactive substances such as nerve growth factor (NGF), epidermal growth factor (EGF), renin, and members of the kallikrein (klk) gene family [ 1- 3].
Seaweeds contain many types of bioactive substances with health benefits that are not easily obtained from land-based foodstuff.
Thus, folic acid and genistein are environmental exposures in the sense that consumers cannot necessarily know how much they are consuming – these bioactive substances are in so many foods, and one cannot tell from how they look or taste or how they are labeled exactly how much of these substances are being imbibed.
Many antimicrobial textiles are treated with combinations of bioactive substances to enhance the antimicrobial efficacy of the finishes and counter act the negative aspects of the treatments.
In the body under physiological conditions, many vital functions are regulated by transient release of bioactive substances at a specific time and site.
