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Third, it is quite difficult to reach the real causal effect of RBCT because of treatment repetitions and of the many baseline- and time-dependent confounding factors.
Significant variation in many baseline clinical and laboratory characteristics among patients with different response category reflects the heterogeneity of multiple myeloma.
However, longitudinal physiological studies of marine mammals are notoriously difficult due to their largely aquatic lifestyle, such that many baseline indicators of health and condition are not well defined.
Disease duration and many baseline disease activity measures were higher in the monotherapy group, consistent with the fact that the majority (72 %) of monotherapy patients were TNFi-IR.
Many baseline imbalances were clinically relevant, and population quintiles, based on a propensity model, were developed to address these imbalances.
As we well know, many baseline parameters including virus, host and drug factors are associated with response to IFN-α-based therapy.
The prospective outcome data and the many baseline risk factors included in the Women's Health Initiative WHII) provide an opportunity to better understand the reasons for this association.
The sets were even at one apiece, but Roddick had secured a third-set service break, was leading, 4-2, asd, as Coach Federer insightfully noted, "Andy was just getting too many returns back," hitting his supposedly vulnerable backhand surprisingly well and winning too many baseline rallies on Federer's serve.
There were significant differences between men and women in many baseline characteristics.
Our matched comparison cohort was identified through propensity scores derived from health insurance claims so that it was not only contemporaneous with the tegaserod initiator cohort, but also was similar to it with respect to many baseline characteristics including demographics, diagnoses, procedures, drugs, and healthcare utilization.
It is possible that loss to follow-up could have introduced bias, but many baseline variables were similar in the study sample and in those excluded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com