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Many agents cause cell cycle arrest without inhibiting mTOR (or other growth factor-sensing pathways).
Current understanding is that many agents cause cancer at multiple sites, and many cancers have multiple causes.
In anti-cancer therapy, many agents cause DNA damage as their mechanism of cytotoxicity, and repair of damage is a cause of tumour resistance.
Current understanding of the mechanisms by which many agents cause occupational asthma is limited, especially for low-molecular-weight sensitizers and irritants.
Although many agents cause IL-6 to be secreted, the overexpression or hypersecretion of IL-6 can be induced by arsenic exposure both in vivo (Das et al. 2005) and in vitro (Lee et al. 2005).
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Healthcare settings have been identified as preferential for the transmission of many agents causing highly infectious diseases (HIDs).
Radiotherapy and many chemotherapy agents cause DNA damage, which may be related to the risk of subsequent neoplasms.
Many different agents cause narrowing of conducting airways (asthma) and some of these cause permanent distortion or obliteration of airways as well.
Anticoagulant response posed by cobra PLA2 (anticoagulant enzyme) may aggravate hepatic injury as many anticoagulant agents cause liver damage that are idiosyncratic in nature [ 36].
And then, we know that from many, many studies that these agents cause mutations in DNA that are seen in genes that we know are involved in cancer".
First, many agents that cause acute gastroenteritis are recognized as known or possible causes of foodborne illness, but because of a paucity of data, the number of agent-specific illnesses cannot be estimated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com