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Poor communication among the care staff has been repeatedly identified as a contributing factor to many AEs [28, 29] and also has been observed in our study.
Many Aes Sedai are captured or killed until Egwene, leading a group of novices, succeeds in driving them off.
Many AEs require supportive therapies (including additional medications), and some require drug holds and/or dose reductions.
Poor communication among the care staff has been repeatedly identified as a contributing factor to many AEs [ 28, 29] and also has been observed in our study.
24 Most reported errors are errors of commission, although chart reviews suggest that acts of omission are implicated in twice as many AEs.
Although unmanageable AEs indicate intolerance to therapy, many AEs observed with front-line and second-line TKI treatment can be managed with supportive care.
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Because many Ae. aegypti genes have yet to be annotated with specific gene functions we attempted to assign a probable function to them by searching several databases (VectorBase, SwissProt, and NCBI) for similar genes with known functions (Table 7).
4 Patient symptoms are often indicators of the amount of harm arising from healthcare, 1 with retrospective medical record review studies detailing a large rate of errors of commission and omission; many causing AEs. 5 6 While a very low percentage of patients with AEs initiate a formal complaint, significant numbers (23 50%) report concerns related to an AE or undesirable events.
However, sunitinib treatment was associated with higher frequencies and greater severities of many common AEs compared with capecitabine.
Many reported AEs and SAEs were indicative of an exacerbation of AS (see online supplementary table S1).
Following Hartmann, we may therefore state that "according to its manner of being, the artistic object necessarily has two levels" (those of foreground and background), while "according to the overall structure of its content that is to say, according to its inner form (i.e. the background level)—it has many levels" (AE; Poli 1998).
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