Sentence examples for many additional targets from inspiring English sources

Although one or a few targets have been identified for a given sRNA, it is likely that many additional targets remain to be found.

ROCK is best known for its role in regulation of the actin cytoskeleton, but it has many additional targets and has been linked to multiple functions including cell motility, establishment of cell polarity, cell proliferation, and cell death [ 112– 112].

Transcription factors that include the differentially expressed enzymes in their target pattern, but have many additional targets that were not differentially expressed in our data set, in contrast, have a low probability to be responsible.

For example, in E. coli, the transcript of the multi-cistronic gal operon was for many years the only known Spot 42 target [ 10], but a recent microarray analysis in which over-expression of spf with an isopropyl β-D-thiogalactopyranoside (IPTG -inducible promoter was used, suggests many addIPTG -inducible [ 11].

We used the complete TCGA BLCA dataset currently available to test the tool and identified 204 potential targeting miRNAs and many additional targeted genes by 79 selected miRNAs.

Many additional target genes that affect actin dynamics were predicted, which further supports a role for miR-145 in regulation of cell motility.

Hence, we expect that many additional cellular targets of insulin will emanate from studies of this kind.

However, the already available information and the development of many additional biologicals targeting IL-6 or its receptor reveal the importance of this treatment option to improve the outcome in patients with RA, JIA and possibly other inflammatory diseases.

However, one cannot lose sight of the fact that these targets exist in the cellular environment consisting of many additional influences on target function, and that effective drug treatment will take into account drug uptake, metabolism and elimination at the level of the cell as well as the organism.

Beyond the network components we identified, many additional let-7 target genes are likely to regulate developmental changes in stem cells, integrating stem cell properties with changing tissue growth and regeneration demands throughout life.

Due to the intrinsic complexity of molecular interactions, besides target proteins many drugs interact with several additional targets, which may lead to unwanted side effects.