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In addition, the availability of cell lines from these samples has allowed many additional studies to be performed, including analyses of copy number variation [6], [7] and gene expression 8, 9, while whole-genome resequencing is now under way (http://www.1000genomes.org/page.php).php
Many additional studies reveal that young learners develop and retain naïve or folk theories of biology or evolution concepts (Hatano and Inagaki 1994; Inagaki and Hatano 2004, 2006; Solomon 2002; Springer 1996).
The studies represent an important step forward towards identifying the self-renewal mechanisms in the adult heart and suggest that microRNAs are major regulators of these processes, but many additional studies are necessary before their therapeutic value for patients can be assessed.
While many additional studies are clearly needed to fully understand it roles in C. perfringens, linkage of the agr locus to PFO and α toxin production opens a new chapter towards understanding toxin gene regulation by the important pathogen C. perfringens.
Since the review in 2002, many additional studies have been published which may provide information on these developmental outcomes.
Many additional studies would be necessary to identify the cellular elements altered by PKC that result in the decrease in EtOH excitation in DA VTA neurons.
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Since that time, many additional clinical studies determining the concentrations of SMRPs in serum and PF have been reported.
Apart from NEPTUNE, many additional cohort studies and randomized trials are ongoing that employ protocols for urine collection and storage.
Since the publication of these two meta-analyses, many additional observational studies have investigated breast-feeding and type 1 diabetes, allowing a new meta-analysis to be conducted on an independent group of more recent studies.
Hence, a point in the discussion by Greenland et al (2000) that 'possibly measures only reflect effects of some biologically relevant exposure that is missing from data.' is still valid after 10 years, despite many additional published studies.
Because MDM2 overexpression and high frequencies of TP53 mutation are found in many tumor types, additional studies on other tumor types would be warranted.
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