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In addition to this known misassembly, REAPR identified many additional putative misassemblies in the M_zebra_v0 assembly.
In addition to identifying eight of the nine known deletions, many additional putative variable regions were identified using either cutoff, with more regions being detected using the less stringent cutoff.
There are also many additional putative RND efflux pumps in this species, but which have not been characterized in resistant strains [4], [19].
A search of the protein databases uncovered many additional putative phosphite dehydrogenases.
Identification of these clusters also led us to identify many additional putative interactions between transcription factors and target genes not included in the known network, and most importantly, enabled us to describe and visualize the activation of regulatory proteins and target genes over time.
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These programs are identifying a large number of additional putative breast cancer susceptibility genes, many of which are currently undergoing validation.
Additional putative heavy metal-responsive genes, many of which are absent in KT2440, F1 and GB-1 (Table 3), can be found on putative genomic islands on the W619 chromosome.
Interestingly, use of FlaFind, a recently developed program capable of predicting Sec substrates with class III signal peptides, not only identified additional putative Sec substrates, but also revealed that many of the SignalP-positive substrates are in fact predicted to contain a class III Sec signal peptide [131].
The full range of these features cannot be reproduced by a kinetic model in which anesthetic acts only by binding to putative protein sites, without having multiple sites with varying affinities, as well as many additional conformational states beyond the canonical set of three (resting, open, and desensitized).
There are many additional reasons.
Samaha has since made many additional millions.
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