Sentence examples for many Wnt signalling from inspiring English sources

Many Wnt signalling species are regulated during differentiation of TGCT-derived EC cells.

Our data fully supports these models, as we also see epigenetic silencing of many WNT signalling antagonists, including notably WIF1 [ 20] and SFRP1 [ 28], the latter also being an unfavourable prognostic marker [ 27].

Many Wnt signaling regulators directly bind to and inhibit the Dvl PDZ domain (Wharton, 2003; Wallingford and Habas, 2005).

Moreover, many Wnt signaling molecules have been implicated in NMJ development, including Dvl and APC (Luo et al., 2002; Wang et al, 2003).

Many Wnt signaling regulators have been reported to mediate the different Wnt signaling pathways by interacting directly with the PDZ domain of Dvl (Wharton, 2003; Wallingford and Habas, 2005; Gao and Chen, 2009).

HMEC cells, used as a normal control, expressed many Wnt signaling genes, including 9/19 (48%) Wnt ligands, 7/9 (78%) frizzled receptors, LRP-5, LRP-6, as well as four LEF/TCF transcription factors.

RAS orchestrates a complicated process during nephron development in the metanephric mesenchyme by regulating expression of various growth factors including many Wnt signaling members such as Wnt9b and Wnt11[ 53].

(We note that RNAseq analysis of STF cells showed low level expression of many Wnt signaling components, including Frizzled receptors, Lrp co-receptors, Gpr124, and Reck [ Zhou and Nathans, 2014], which likely accounts for the signals observed when individual components are omitted from the transfection).

There are many Wnt-dependent signaling events, but only one pathway has so far been associated with the stem cell functions and oncogenic properties.

Wnt signalling regulates many developmental processes in metazoans, including cell proliferation, migration and pattern formation [ 1].

Wnt signalling has many roles in animals, and defects in it can contribute to cancer and other devastating diseases.