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In this manuscript we lay out a maximum likelihood framework and an accessible software implementation for estimating an organism/gene specific evolutionary model and alignment scoring matrix, describe common techniques for validating the model and infer a model from a large collection of HIV-1 sequences.
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We lay in parallel furrows.
We lay clothed in her narrow bed.
We lay as flat as flounders".
We lay on rotten, piss-smelling straw.
We lay our plans.
We lay out the evidence.
We lie there, heaving.
Are we lying to our viewers?
Here in the static dark we lie.
We lie for survival!
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CEO of Professional Science Editing for Scientists @ prosciediting.com