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The evidence presented in the manuscript points to the fact that neural systems should not be seen as a seat of optimal processes and circuits addressing particular problems in sensorimotor cognition, but as a set of satisficing and tinkered components, mostly not addressing the problems that are supposed to solve, but solving them as secondary effects of the engaged processes.
3) In addition, the manuscript points out that a variety of models are able to fit age-specific incidence or prevalence data so conclusions may be a function of model structure rather than biological fact.
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Nevertheless, we added two sentences to the manuscript, pointing at this coincidence as suggested by the reviewer.
We have added a sentence to the manuscript pointing this out (please see the subsection headed "Changes in synaptic activity alter the recycling pathway taken by AMPARs").
As the authors for this manuscript point out, virtually all of our previous "disaster plans, including those in hospitals were woefully inadequate and failed miserably [ 3].
William Stingone, the library's Charles J. Liebman curator of manuscripts, pointed to a 19th-century book from the Emigrant Savings Bank in the library's collection, which included the birthdates, occupations and other information on depositors.
One of the very first features I ever wrote rashly enquired why women dominated fiction but rarely wrote plays: I was deluged with letters, and manuscripts, pointing out the reasons were entirely circumstantial and determined by the fact the theatre was largely governed by male tastes.
Since 2002, several manuscripts pointed to the existence of MLH1germline methylation [ 15- 21].
VT: Changes on the final version of the manuscript, additional points included in the discussion.
But as the review of the original manuscript correctly points out, it is absolutely the case that this is not the only possible explanation.
(That spirit floats through the current exhibition at the Morgan Library on Wilde, which displays letters and manuscripts chronicling points at which Wilde and Robertson's lives intersected).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com