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Although this manuscript has focused on the analysis of technical replicates, dependence must also be taken into account in longitudinal studies and designs in which the class assignments associated with subject replicates are potentially different.

Although this manuscript has focused on the underlying structure of tasks, the analysis does suggest a prediction regarding neural activity of animals performing episodic memory or working memory tasks.

For this reason, the scope of the current manuscript has focused on extending our analyses specifically to comparison with in vivo protein co-expression networks.

This manuscript has focused on the utility of different LYVE-1 antibodies as routine markers for detecting and quantitating lymphatic vessels in breast cancer.

It is important to point out that while this manuscript has focused on the Snf2-dependent changes to chromatin structure at centromeres, additional changes are evident elsewhere in the genome in our data set (data not shown).

Similar(55)

However, such analyses represent a long-term project, beyond the scope of the current manuscript, which has focused on mechanistic studies using Teff cells.

has focused on reducing costs.

In the present manuscript, we have focused to study the gene expression profiles of biopsies collected from patients with squamous cell cervical carcinoma of different FIGO stages (FIGO News, 1987) in comparison to the adjacent histo-pathological normal epithelium.

As discussed in our first revision in response to Referee 1, in this manuscript we have focused our attention on the simultaneous alteration of both upper and lower jaws of Dlx5/6 double mutant embryos.

In the previous version of the manuscript, we had focused our attention solely on the reversal of this temperature-size rule below the lower thermal limit, which has been reported previously only in protists and in Drosophila (Karan et al., 1998; Atkinson et al., 2003), and hypothesized to be driven by restricted aerobic metabolism below the lower thermal limit.

We have thought carefully about the criticisms of all the referees, and have focused and simplified the manuscript as a consequence.

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