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Monica Neufang, a company spokeswoman, said, "Our third-party manufacturer has had some manufacturing issues related to capacity".
McNeil has been beset by recent manufacturing issues.
But the F.D.A.'s recent letter said officials remained concerned about continuing manufacturing issues at Apotex.
The F.D.A. has entered into consent decrees with other pharmaceutical companies in the past for manufacturing issues.
Last year, the Food and Drug Administration halted recruitment of new patients to the clinical trials because of manufacturing issues.
Indeed, investors' enthusiasm extended to other industrial and manufacturing issues, including 3M, which gained $2.81, to $112.86.
The House committee is trying to determine the chronology and the cause of the manufacturing issues at Johnson & Johnson and whether federal regulators responded adequately.
In February 2005, the F.D.A. issued an "approvable" letter, which Discovery said meant that the drug would be approved as soon as it ironed out some manufacturing issues.
What is most perplexing is the seeming inability of executives to solve — and satisfactorily explain — the manufacturing issues that dog the company.
Stocks rose yesterday in sparse volume, led by financial and manufacturing issues as some investors bet that rising borrowing costs will trim, but not slash, corporate profit growth.
SkyePharma chief executive Michael Ashton said that "manufacturing issues" had been resolved and hopes were high that the drug would be very successful.
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CEO of Professional Science Editing for Scientists @ prosciediting.com