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About 7% of available GIRO ionograms underwent a labor-intensive process of manually validating the autoscaling results.
The analysis involved examination of each of the matched term pairs that had been identified by various approaches in the preliminary work, and then manually validating the matching.
We believe that the extra step of manually validating these isoforms is justified because only an accurate and detailed plasma proteome can serve as a reference for future biomarker discoveries and diagnostic applications.
After manually validating the 11 spectra by taking a close-up view of their MS/MS spectra and tracing back to the corresponding MS spectra, we found all of the 11 query spectra were co-eluted spectra and their identifications by the two engines caught different components.
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To palliate the increasing time required to manually validate large proteomic datasets, we provide computer aided manual validation software (CAMV) to expedite the process.
All hits from the search were manually validated and confirmed by manual MS/MS spectral assignment.
54511 were also manually validated.
We only used the subset of compounds that were manually validated.
MWN.PT (version 1) spans over 21,000 words and 17,200 manually validated synsets.
Orbit propagator software generated 20,524 coincidence time intervals for which manually validated EDPs were requested from the DIDBase.
It is expected that publications using manually validated data retrieved from the GIRO archives include the data proprietor as a co-author.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com