The phrase "manually designed" is a correct and usable part of a sentence in written English.
For example: "The intricate chair was manually designed by the master woodworker."
If no CAPS were previously designed from our SNP set, CAPS markers were manually designed with CAPS Designer (http://solgenomics.net/tools/caps_designer/caps_input.pl) and Primer3Plus (http://www.bioinformatics.nl/cgi-bin/primer3plus/primer3plus.cgi/).
When the sequences are manually designed this knowledge comes from a human brain, aided by manual lookup of literature and databases.
Unlike existing feature-based methods, this approach does not rely on any manually designed features.
The network topology was manually designed, and then modified in response to observed difficulties during evolution.
Therefore, NerOne automatically combines the components instead of using manually designed rules.
Research in the past was based on manually designed screens with minimal software support.
Then the components are combined to build final irregular entities according to manually designed rules.
Although contact burns were frequently used models, most of them were manually designed.
A manually designed motor driver was also embedded to the actuator module.
Firstly, a reasonable AI operating at Ku band was manually designed using a 130 nm technology.
Then a set of manually designed filters are utilized on the new channels to generate more response feature maps.
