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In the CTD, such information has been manually curated for the chemical-gene interactions.
The alignments were manually curated for ambiguously aligned sequences compared to the 3D-structure alignment.
This cell size interval was visually inspected and manually curated for all mutants.
These genomes were manually curated for correct methionine initiation and redeposited with a total of 1885 homogenized genes.
The procedure described above automatically generated the TAED database and hits were manually curated for this study.
Another option is to center on active atoms, but these need to be manually curated for the most part.
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These annotations are manually curated from literature previously curated for rat strains and quantitative trait loci at RGD.
A total of 61 530 articles were manually curated: 51 884 for drug disease and 9 646 for drug phenotype (Table 2).
At the interaction level, a total of 254 173 interactions were manually curated: 183 849 for drug disease and 70 324 for drug phenotype (Table 2).
Although RefSeq does contain manually curated genomes for some organisms, many annotations for bacterial genomes are listed as "provisional", meaning that they have not yet undergone final review by NCBI staff.
Both the STEM and FBPA methods showed lower agreement with the manually curated standard for qRT-PCR data than for microarray data as shown in the first row of Table 1, but the STEM clustering performed noticeably more poorly (0.607, 0.661 vs. 0.486, 0.483).
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CEO of Professional Science Editing for Scientists @ prosciediting.com