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Among the databases that receive manual review, maintaining manually curated data can present a challenge.
There is a need for tools which can assist curators in persisting manually curated data through the update process either through automation or by providing pipelines for the transfer of manual annotations of these databases.
WikiPathways contains both manually curated data (provided by the pathway curators) and imported pathway data from NetPath, KEGG, etc.
The International Molecular Exchange (IMEx) consortium can be considered the key public curator of such data, focusing on manually curated data to ensure the high-quality datasets that are required for further analysis [ 48].
Figure S2 (now S1.2) is an estimation of orphan enzymes at the superkingdom level based on non-curated data from FRENDA and AMENDA whereas Figure 6 was made using manually curated data.
Therefore, we standardised the algorithmic output to enable comparison between algorithms and with manually curated data.
The platform comprises of manually curated data on antimycobacterial natural products along with tools to perform structure similarity and visualization.
Identifying molecules and drugs with known or predicted targets [35] involved searching the CDD databases for manually curated data.
In addition, literature-based manually curated data, transcriptome data, and NGS data of major rice cultivars were also incorporated into the database.
This indicates the high quality of patent-mined data, which is similar to that of manually curated data from the literature.
Compounds with inhibitory activity measured against BCRP and/or P-gp were retrieved by combining Open Data and manually curated data from literature using a KNIME workflow.
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