In the Philippines, we hired two full-time people to manually calculate and file the infinite (at least that is what it felt like) number of forms and remittances with the government.
Automated and manually calculated PPV and other hemodynamic data were recorded before and after fluid administration of 500 ml of 6% hydroxyethyl starch (130/0.4) over 30 minutes.
The agreement (mean bias ± SD) between automated and manually calculated PPV was 4.03 ± 7.37%.
Active control group (CNL) patients received enhanced usual care and manually calculated bolus insulin dosages according to individualized parameters.
The aim of this study was the assessment and comparison of the ability of automated PPV, when measured by an IntelliVue MP 70 monitor, and manually calculated PPV to predict fluid responsiveness in mechanically ventilated septic shock patients.
Automated PPV and manually calculated PPV were significantly higher in responders than in nonresponders (16.0 ± 4.5% vs. 7.2 ± 2.0% and 11.1 ± 5.6 vs. 4.6 ± 2.8%, respectively; P < 0.001 for both).
Our results indicate that the automated PPV, obtained by the IntelliVue MP 70 monitor, and manually calculated PPV, showed comparable performance for predicting fluid responsiveness in passively ventilated septic shock patients.
For cyclin A, images were captured in a similar way; however, a labelling index (defined as the ratio of positive to negative nuclei) was manually calculated for each section and a mean at each duration of ischaemia was expressed relative to time point zero.
Measurement errors of under ±2% are obtained between what the machine indicates and the manually calculated length.
However, our findings were supported by the good agreement between the two independent investigators, and by the concordance also observed between the automatically calculated NeuroSync index and the manually calculated PVA.
