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The CGC contains extensive and manually annotated information on well-known cancer genes and classifies the cancer genes into dominant (Dom) and recessive (Rec) influence on tumorigenesis.
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This highlights the importance of using text mining for a comprehensive retrieval of information, complementing manually annotated data, which may potentially miss over 1,700 TC-related genes (84% of 2,071).
Modern automated information extraction (IE) systems usually are based on machine-learning models, which require large amount of manually annotated data to specify the model according to the task at hand.
The manually annotated data will test the exactitude of our classifier.
It offered manually annotated data that allowed participating researches to improve and evaluate their tools.
A complete description of the manually annotated data used for evaluation can be found in [31].
Thus, we manually annotated this information within the data.
Genes in the Hox gene complex (HOM-C) and five other gene complexes were searched in silico in the D. buzzatii genome and manually annotated using available information (Negre et al. 2005), the annotated D. mojavensis and Drosophila melanogaster genomes, and the RNA-seq data generated for D. buzzatii (Negre B, Muyas F, Guillén Y, Ruiz A, in preparation).
Source A: UniProtKB/Swiss-Prot [ 23, 24] refers to a particular section of UniProtKB that presents manually annotated and reviewed information.
To best of our knowledge, this is the first work where manually annotated corpora containing information about miRNAs and miRNA-relations are published.
The curators of the Gene Ontology Consortium manually annotate this information.
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