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Following this manual registration over the dynamic series, the ROI was used to construct a nine-point signal intensity curve as a function of time.
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The linear affine transformation (in combination with a subsequent landmark-guided manual registration) was selected over non-linear transform methods to minimize loss of signal due to warping, which is relatively greater in the small subcortical regions [68] relevant to our a priori hypotheses.
The user interface was designed to support the manual registration of the images.
FIRE was successfully applied to many clinical cases for which automatic and/or manual registration was required.
Marker-free manual registration.
(a) (Manual registration) (b) (Automatic registration).
Manual registration (with mutual information).
(a) Evaluation (Manual registration) (b) Test (Manual registration) (c) Evaluation (Automatic registration) (d) Test (Automatic registration).
User specific-registration obtains better results than user-independent registration and manual registration.
Of the three registration methods tested, manual registration was most accurate.
Of the three tested registration methods, manual registration was most accurate.
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