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In whole roots, these proteins are expressed in a coordinated manner with strong transcriptional induction in response to Fe deficiency.
Because of the special requirement to compete with traditional vehicles, EVs must develop in a step-wise manner with strong closed-loop control.
As expected, hFcRn was shown to bind WT huE6F6 and Fc mutants in a strictly pH-dependent manner, with strong binding at pH 6.0 but reduced interaction at pH 7.4 (Fig. 1B).
Similarly, α-tomatine also inhibited TNF-α-induced NF-κB activation in a dose-dependent manner with strong inhibition observed at 2.0 µM treatment (Figure 8A, and 8Biii).
Subsequently, expression is shut down in a tissue-specific manner with strong transcription maintained only in the retina and mid-hindbrain boundary beyond 24 hpf (data not shown).
Preincubation of HeLa cells with compound Ia prevented the downregulation of IκB by TNF-α in a dose-dependent manner, with strong effects at concentrations as low as 10 nM (Fig. 4B), an evidence of its activity as an antagonist of NF-κB activation induced by TNF-α in these cells.
Similar(52)
Job strain was associated with AF risk in a time-dependent manner, with stronger association after 10.7 years of follow-up (HR 1.93, 95% CI 1.10 3.36 after 10.7 years, versus HR 1.11, 95% CI 0.67 1.83 before 10.7 years).
Now 22, Woodhouse combines his gentle manner with a strong determination.
Possible reasons included poorer public health infrastructures and human and financial resources, organisational structures that functioned mainly in a top-down manner with a strong emphasis on structures more than functions, and lack of planning initiatives the further away one moved from central level [76].
Published content fulfills the founders' expectation of addressing a global health agenda in a creative, constructive, and relevant manner with a strong focus on policy and implementation (2).
This surveillance-based study showed increasing ASD prevalence associated with increasing SES in a dose-response manner, with a stronger SES gradient in ASD prevalence in children with versus without a pre-existing ASD diagnosis.
Related(20)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com