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For astrocytes, chemokines IL-8 and CXCL-1 were secreted in time-dependent manner, with peak secretion at 24 h after cell stimulation compared with unstimulated control cells.
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While the spread rate in concurrent spread increases linearly with free-stream velocity, the spread rate in opposed flow varies with free-stream velocity in a non-monotonic manner, with a peak rate at an intermediate free-stream velocity.
As seen in Figure 7 upon injection of the veratridine the muscle began to contract in an asynchronous, tetanic manner with a peak stress far beyond those of the synchronized contractions.
Preliminary data obtained by EMSA showed that nuclear extracts from untreated Raji cells had a basal level of AP-1 DNA-binding activity and p17 activated AP-1 DNA-binding activity in a dose-dependent manner with a peak at 1 µg/ml dose (data not shown).
We observed that Ang II stimulation for 1 hour resulted in a dramatic increase in the formation of O2− and ONOO− in a dose-dependent manner with a peak of O2− and ONOO− production at concentration of 0.5 µM and 2 µM of Ang II respectively.
P2Et fraction and doxorubicin can induce a slight increase in MCP-1 secretion by 4T1 cells in a dose-dependent manner with a peak at 48 h.
Furthermore, studies in tobacco cell culture have shown that telomerase activity is regulated in a cell cycle dependent manner with a peak level in S-phase.
The stimulation of epithelial cells by LPS highly activated PLCγ1 in a temporal manner with its peak expression at 4 h.
In order to clearly separate the patient samples by bimodal gene expression, we normalized the signals, so the signals could be presented in a binary manner, with one peak designated as -1 and another as 1.
Overall, these studies suggest that large volumes of saline will increase the chloride concentration and reduce base excess in a dose-dependent manner, with the peak effect occurring a few hours post infusion.
In mammalian cells, Nlp (also named as Nlp isoform A by van Wijk et al) is expressed in a cell-cycle-dependent manner with a peak at G2/M transition.
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