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The principle of virtual work and a finite element approximation are used to formulate the governing equations in a total Lagrangian manner, whereas a Newton Raphson linearization scheme along with a path-following method based on the arc-length constraint is employed to solve the geometrically nonlinear problem.

A 14-mer peptide (17 30) encompassing this sequence was capable of reducing food intake in a dose-dependent manner whereas a peptide designed on a more C-terminal region (211 232) of apoA-IV (QEKLNHQMEGLAFQMKKNAEEL) failed to exhibit the dose-dependent anorectic effect.

Synthetic IRNA was found capable of replacing the radiolabeled 5'UTR portion of GLV IRES from binding to recombinant GlLa protein in a dose dependent manner, whereas a non-specific RNA of similar size did not exert any detectable effect (Fig. 3B).

As shown in Figure  4 (bottom and right panels), lentiviral infection reduced cell viability in a dose-dependent manner, whereas a GFP control construct resulted in no significant changes in cell viability (Additional file 14).

In a Swedish prospective study, pre-diagnostic calcium serum levels were inversely related to premenopausal breast cancer in a dose response manner, whereas a high level of calcium indicated an increased risk among overweight peri/postmenopausal women [ 45].

As reported in intact cells, the FYVE domain peptide inhibited LC3 lipidation in a dose-dependent manner whereas a cysteine to serine (C/S) mutation, which abolishes the ability of FYVE to bind PI3P, had no effect on lipidation.

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An online algorithm tackles a given problem instance in a sequential piece-by-piece manner, whereas an offline algorithm approaches the problem at hand as a whole, considering the relevant interdependencies of its parts [ 40].

34, 35 Afunctionsons in a hormone-independent manner, whereas AF2 function requires the presence of a ligand.

We also find that when the silver ion concentration is 1.00 mM the electrodeposition is via adsorption in a well-defined manner, whereas at a concentration of 0.005 mM the mechanism involves three-dimensional nucleation and island formation.

The results were that Lp(a) significantly stimulated the growth of human VSMC in a dose-dependent manner, whereas ox-Lp(a) showed a stronger stimulatory action on VSMC growth than native Lp(a).

Thus, both SA and ET regulate WRKY25 expression in a positive manner, whereas JA has a negative effect on WRKY25 expression.

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