Senescent neutrophils homing back to the BM in a CXCR4-dependent manner are subsequently phagocytosed by resident tissue macrophages (4, 12).
Two zebrafish strains, C32 and SJD, were generated in this manner and were subsequently inbred for a number of generations (Johnson et al. 1995; Nechiporuk et al. 1999; Streisinger et al. 1981).
Thus, some of these novel polymorphisms may actually represent low penetrance modifiers of ovarian cancer risk, in a similar manner to BARD1 polymorphisms that were subsequently shown to be associated with increased breast cancer risk in the general population [ 37- 39].
Inhaled pathogens such as Mycobacterium tuberculosis [31], [32] and Pseudomonas aeruginosa [33] were phagocytosed by macrophages in a C3-dependent manner to be subsequently cleared by the lungs.
During mouse pre-implantation development, extra-embryonic primitive endoderm (PrE) and pluripotent epiblast precursors are specified in the inner cell mass (ICM) of the early blastocyst in a 'salt and pepper' manner, and are subsequently sorted into two distinct layers.
One explanation for the observed range in severity of the root growth defects is that the distinct mutant combinations represent an allelic series of sorts, with each reducing exocyst complex function in a quantitative manner, which is subsequently manifested in quantitative effects on root growth rate.
Phosphorylated β-catenin is recognized and ubiquitinated by E3-ubiquitin ligase β-TrCP in an APC- (adenomatous polyposis coli) dependent manner and is subsequently degraded rapidly through the proteasome (Hart et al, 1999; Liu et al, 1999; Rubinfeld et al, 1993; Su et al, 2008).
These naturally laid eggs were subsequently handled in similar manner to those from artificial crosses after fertilization.
All of the IPV intervention facilitators and nurse instructions were subsequently formatted in a manner consistent with current NFP guidelines.
The standby and reallocated practices were subsequently randomly allocated in a similar manner.
