Sentence examples for manner we tested from inspiring English sources
To explore if HIF2α expression was regulated in a more indirect manner, we tested the effect of blocking protein translation by cycloheximide (CHX) in conjunction with Notch activation.
Since Mcl1 physically interacts with Polα and associates with chromatin in a G1/S-phase specific manner, we tested whether the Mcl1 foci formed during S-phase corresponds to replication factories.
In order to examine whether or not bilateral tool transfer was maintained in a short-term reciprocal manner, we tested the mothers and offspring in a situation in which they could not expect any short-term reciprocation from the partner.
In a blinded manner, we tested each sample 15 times (5 tests each on three separate days).
In the same manner we tested heterogeneity in the trend estimates for mothers by age at diagnosis in daughters.
As CTCF often binds DNA in a methylation-sensitive manner, we tested whether the in vitro methylation of these two sites in R30 affected CTCF binding.
To further analyze TRPV4-mediated mechanisms in vascular endothelial function in a more definitive manner, we now tested shear stress and agonist-induced endothelium-dependent vasodilation in mice lacking the TRPV4 channel [24].
In the same manner, we also tested if the concentration-response effect differed between the isoforms.
To confirm these findings in an independent manner, we also tested whether depletion of the microtubule depolymerases KIF2a/MCAK would allow 2 1 cells to enter anaphase with asymmetric spindles.
However, having established that the M705V mutation affected the binding of both CHIP and the cSti1 in a predictable manner, we next tested the binding of Tah1 and, as expected, we found that the M705V mutation inhibited the binding of Tah1 (Kd=13±1.7 μM) relative to wild-type protein (Kd=0.78±0.06 μM; Figures 1a and 6e).
As MGCD inhibited HDAC1, HDAC2 and HDAC3 in a dose-dependent manner, we then tested the effects of MGCD at different concentrations, showing that the neurospheres became larger as MGCD concentration increased and about 90% of the neurospheres were larger than 200 μm in diameter when MGCD was used at 0.5 μM to 1.66 μM.
