Sentence examples for manner regulated by from inspiring English sources

Our recent data shows that Flii is secreted from macrophages via late endosomes/lysosomes in a manner regulated by Rab7 and Stx11.

For example, MAL, a cofactor of the transcription factor SRF, cycles dynamically between the nucleus and cytoplasm in a manner regulated by its binding to G-actin in quiescent cells (Miralles et al., 2003; Vartiainen et al., 2007).

These changes, including both reversible and irreversible ones, are not an all-or-none phenomenon, but are finely graded in a context-dependent manner regulated by specific signaling pathways [ 87].

We used a phylogenetic approach to identify putative functional regions within the sequence of Repo-Man, a targeting protein that binds PP1 in a cell-cycle specific manner regulated by a phospho-switch (Trinkle-Mulcahy et al., 2006; Qian et al., 2011; Vagnarelli et al., 2011).

A second region at the extreme carboxyl (C) terminus of vertebrate Brca2, unrelated in its sequence to the BRC repeats, binds Rad51 [25, 25] in a manner regulated by the phosphorylation of a key serine residue (Ser3291 in human BRCA2) by cyclin-dependent kinases (CDKs) [26].

Instead, reactive astrogliosis is a finely gradated continuum of changes that occur in context-dependent manners regulated by specific molecular signalling events.

It is now clear that reactive astrogliosis is not a simple all-or-none phenomenon but is a finely gradated continuum of changes that occur in context-dependent manners regulated by specific signaling events.

BMPs may act in an autocrine or paracrine manner, being regulated by specific antagonists, namely: noggin and chordin.

These results suggest that PLD1 has the capacity to associate with CtBP1/BARS in a manner reversibly regulated by serum.

Taken together, these results demonstrate that we have obtained a suitable cell source of sRANKL which can be used for our biotechnological approach in a manner physiologically regulated by hormonal factors, such as the PTH.

The majority of characterized uORFs appear to act in an amino acid sequence-independent manner, regulating mORF translation by the uORF start codon nucleotide context, by the uORF length, or by the distance between the uORF stop codon and the mORF start codon, rather than by uORF-encoded peptides [ 8- 11].