It showed that ZnO NPs activated in the cells in a manner of dose-effect relation and had more obvious function to the HEK293 cells (p < 0.01).
The MTT results showed that EGCG nanoliposomes and EGCG activated in the cells in a manner of dose-effect relation and EGCG nanoliposomes had a more obvious function to the tumor cells (p < 0.01) without affecting normal cell viability.
The methyl thiazolyl tetrazolium results demonstrated that Lf nanoliposomes and Lf activated in the cells in a manner of dose-effect relation and Lf nanoliposomes had a statistically significantly different (p<0.01) between the concentration 5 and 10 mg/mL.
The MTT results showed that Lf nanoliposomes and Lf activated in the cells in a manner of dose-effect relation and Lf nanoliposomes has a more obvious function to the cells (p<0.01).
Thus, the concern of drug safety will increase with regard to the possible contraindications, manner of dosing and drug interactions of analgesics [25].
However, since sucralose increases insulin secretion in a dose-dependent manner, high dose of the compound may aggravate hypoglycemia.
Because GSK-7975A mareducedreduced all parameters of pathobiologic response in a dose-dependent manner, a high dose of GSK-7975A and separately CM_128 was begun at 2 different time points after disease induction to determine the effect of early vs late drug administration.
The results of the present study demonstrate that PSI values decrease in a dose-dependent manner with increasing dose of fentanyl and respiratory depression was not observed even with an increase in the fentanyl dose to 20 μg.
The plasma concentrations of FT, 5-FU, CDHP, and Oxo increased in a dose-dependent manner at a dose of 65 or 80 mg/m S-1 with the co-administration of 100 mg/m nab-paclitaxel.
Glucocorticoid therapy has been shown to suppress big IGF-2 in a dose dependent manner using doses of 30 60 mg/d of prednisolone or 4 mg/d of dexamethasone [ 43].
