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In the traditional project processes which don't use building information modeling, the data generated through the project life cycle is typically stored in a fragmented manner in multiple formats.
We have shown that the expression of clusters of genes varies in a development-dependent manner in multiple human tissues.
22 ML240 induced caspase activity in a dose- and time-dependent manner in multiple colon cancer cell lines.
Candidate genes were enriched for genes expressed in a circadian manner in multiple tissues with regulation driven mainly by transcription factors BMAL1 and REV-ERB α, β.
Prior research noted that AMG 900 blocks phosphorylated histone H3 in a dose-dependent manner in multiple human tumor xenograft models 11.
When we considered individual components of the score, we found that E-box binding, circadian protein expression and PPI with clock genes to be the most significant predictors of genes transcribed in a circadian manner in multiple tissues (p<0.001), though RRE binding also played a, albeit less significant, role (p<0.01).
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Here we showed that MLN4924 effectively induces autophagy in both time- and dose-dependent manners in multiple human cancer lines, indicating a general phenomenon.
Here we report that MLN4924 effectively induced autophagy in both dose- and time-dependent manners in multiple human cancer cell lines.
We find GTCpFE to effectively inhibit NFκB activation in a breast cancer subtype-independent manner demonstrated in multiple breast cancer cell lines and the intrinsic NFκB activity essential for CSCs.
Further, it is worth emphasizing that these experiments reveal general tendencies in the manner in which multiple mutations interact that can be extremely weak.
In particular, Risch (1990) considered two different models for the manner in which multiple genes act together to influence risk of a complex disease trait and explored their implications in the context of linkage analysis.
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