Sentence examples for manner in cell from inspiring English sources
In addition, EDTA has been shown to induce shedding of the Notch receptor (S2 cleavage) and thereby signaling (S3 cleavage) in a ligand-mimicking manner in cell systems [47], [48].
β-catenin protein expression, using Western blotting showed a single band (∼94kDa) in a protein concentration dependent manner, in cell lysates from both 1542-CP3TX and 1542-NPTX cells (Fig. 2B).
E2 increased FN mRNA and protein levels in a time-dependent and dose-dependent manner in cell supernatants and ECM.
We also found that the related compound rilmenidine increased autophagy in a dose-dependent manner in cell culture.
The present research demonstrates that apelin/APJ inhibits the osteoblastic differentiation of AVICs in a dose-dependent manner in cell culture.
Spermine decreased the mitochondrial membrane potential and allowed cytochrome c release in a dose-dependent manner in cell free mitochondria preparations [ 93].
We found that Kir6.2/SUR2A (the cardiac-type KATP) channels were activated by cGMP-selective phosphodiesterase inhibitor zaprinast in a concentration-dependent manner in cell-attached patches obtained from HEK293 cells, an effect mimicked by the membrane-permeable cGMP analog 8-bromo-cGMP whereas abolished by selective PKG inhibitors.
Although phosphorylated Chk2 was not detected in H1299 cells treated with empty vector and cisplatin, it clearly increased in a time-dependent manner in cells treated with NPRL2 or NPRL2 with cisplatin.
Probably either the signal for caspase 3 activation was too weak or the pathway of apoptosis was activated in a caspase 3 independent manner in cells growing on permeable inserts.
In this way, DNA constructs can be analyzed in a highly automated and parallel manner in cell-free systems prior to their transfection into CHO cells for subsequent large-scale in vivo production.
After a directed screen against a small library of bisphosphonates, they found several that inhibited relaxase in vitro and inhibited conjugation in a relaxase and F-plasmid-dependent manner in cell-based assays.
