Sentence examples for manner during progression from inspiring English sources
Most epithelial cancers follow a progression scheme in which initiated cells progress to adenomas to adenocarcinomas and metastasis, accumulating genetic alterations in a stepwise manner during progression [6].
Although accumulating evidence indicate that expression of Cav-1 is altered in a stage-dependent manner during progression of various types of cancers [1], [2], [3], [4], the precise roles of Cav-1 in cancer development, progression, and treatment remain to be fully defined.
As a matter of fact, the different nailfold microvascular abnormalities are not all present at the same time but are expressed in a dynamic manner during the progression of the SSc microangiopathy [ 9].
Because UNC5C and DCC both serve as dependence receptors for netrin-1, we investigated whether defects in these receptors accumulate in a systematic or stochastic manner during the progression of gastric carcinoma.
De-regulation of each of these processes represents a rate-limiting step for tumour development and, hence, has to be achieved by tumour cells in a highly selective manner during tumour progression.
On the other hand, upregulation of the miR-103 and miR-194 levels in DCKO mouse sera occurred in a stepwise manner during the progression from normal to early-stage DGC and finally to advanced-stage DGC, suggesting both of them are very suitable biomarkers for DGC diagnosis.
In conclusion, our data reveal that the pathogen C. albicans regulates central carbon metabolism in a niche-specific manner during disease establishment and progression.
3) Regarding the low levels of ATF4 mRNA preferential translation: Assuming that all mRNAs identified in this study operate in eIF2-dependent manner, their translation efficiency is likely to change during progression of the stress for the reasons we outlined above.
However, the manner in which these diverse pathways are integrated into cellular circuitry and regulated during progression of ADPKD is not well studied.
"Darting" was defined as having higher acceleration during progression segments while moving less during stops.
SIX1 mRNA and protein levels increase during progression from HKc/HPV16 to HKc/DR [76],[76].
