Sentence examples for manner demonstrating that from inspiring English sources

COS cells transfected with porcine CD80 was able to activate human T cells in a cyclosporine independent manner, demonstrating that porcine CD80 can costimulate human T cells.

However, in the HC group, the mitochondrial ATP levels in PMNs decreased with fMLP stimulation in a dose-dependent manner, demonstrating that the mitochondrial ATP was consumed in this process in healthy PMNs.

Here, we show that LhrA acts to down regulate the expression of lmo0302 and chiA at the post-transcriptional level in an Hfq-dependent manner, demonstrating that LhrA is a multiple target regulator in L. monocytogenes.

AII increased luciferase activity in a concentration dependent manner, demonstrating that AII promoted NHE3 gene transcription.

Pmp21 coated latex beads are endocytosed in an EGFR-dependent manner demonstrating that Pmp21 is sufficient to trigger invasion [ 12].

Crucially, neutrophil coincubation with MCMV-infected fibroblasts dramatically reduced the production of replicative virions in a cell-number-dependent manner, demonstrating that neutrophils directly inhibit MCMV replication.

The temperature dependencies of the data obtained in this manner demonstrate that the viscosity of PBMA rises upon cooling as expected according to the WLF equation, whereas the increase is lower by several orders of magnitude for PMMA and PVAc.

Moreover, the assessment of MMP, the determination of intracellular free Ca2+ concentration, the production of ROS, and the effects on the activity of caspase-3 in a dose-dependent manner demonstrated that compound 21 induced cell apoptosis in HepG2 cells through the Ca2+/ROS-mediated mitochondria/caspase-dependent apoptosis pathway largely.

Besides, the inhibition of uptake of folate-decorated CNPs by free FA in a dose-dependent manner demonstrates that the particle uptake is mediated by the FA receptor (Fig. 7c).

Recently, Hu et al. provided evidence for a possible molecular mechanism for how the G-allele of SNP309 could accelerate tumor formation in this gender-specific and estrogen dependent manner, by demonstrating that the primarily female-specific hormone, estrogen, preferentially stimulated transcription of the MDM2 gene with the G-allele of SNP309 [20].

25– 27 This study extends these observations in an important manner by demonstrating that reversal of this barrier defect can attenuate the disease, implying that the increased permeability is not simply an epiphenomenon but rather is an important aetiological event.