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Our results thus suggest that although gene expression in some manner constrains mammalian protein evolution, it is less effective at doing so in mammals than in yeast.
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Its membrane-proximal domains of α- and β-subunit interact in a default manner, constraining the integrin in a resting low affinity conformation to its ligands.
That is, they had interpreted and applied the guarantees of the Constitution in a manner that constrained the majority's power to disregard the rights of those who cannot effectively protect themselves in the political process.
DOI: http://dx.doi.org/10.7554/eLife.06034.038 In summary, we showed that highly conserved SLiMs are used in a context-dependent manner for constraining the interaction potential of Hox proteins with surrounding TFs.
It stars Cynthia Nixon, who portrays the poet as a lacerating lampooner of the New England mores and manners that constrained her life and impeded her career.
In this manner subjects were constrained to breathe with their mouth (see SM-A).
For many therapeutic applications, it is desirable to affect neurons promptly (e.g., to terminate epileptic seizures), in a regionally constrained manner to reach maximum on-target effects and reduce effects on unintended brain networks4,5.
Motif enrichment analysis of ChIP-seq data sets indicated that sequence-specific TFs can be recruited in a spatially constrained manner around MyoD1-binding sites.
He has a halting speaking style and the subdued manner of a man constrained by temperament, training and the peculiar fetters of his public duty.
Building new advanced multimedia telecommunications services in a distributed and heterogeneous environment is very difficult, unless there is a methodology to support the entire service development process in a structured and systematic manner, and assist and constrain service designers and developers by setting out goals and providing specific means to achieve these goals.
In this technique, position estimation is performed by each node in an iterative manner by solving spatially constrained local programs.
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