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The sugar sulfanilamide derivative binds to the enzyme in a totally new manner as compared to other CA inhibitor adducts investigated earlier.
Mannose- and N-acetylglucosamine-containing glycopolymers were shown to specifically target mouse bone marrow-derived macrophages (BMDMs) in vitro in a dose-dependent manner as compared to a galactose-containing glycopolymer (30- and 19-fold higher uptake, respectively).
To determine whether measures of ovarian reserve differ between females exposed to cancer therapies in a dose-dependent manner as compared with healthy controls of similar age and late reproductive age.
Very low k values will restrict the domain of applicability in a very strict manner as compared to the AD derived opting for larger k values.
From our investigation, it was observed that methanolic extract of Typha elephantina at two different doses (200 mg/kg and 400 mg/kg body weight) demonstrated a significant reduction of writhes in mice in a dose-dependent manner as compared to control (distilled water).
Wild type BRCA1 increased the expression levels of Flag-Smad3 protein in a dose-dependent manner, as compared to the control caTβRII (Figure 2B).
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Figures 2(a) and 2(b) show that long-term treatment with the NO donor significantly enhanced the motility of the cells in dose- and time-dependent manners as compared with the H460 control cells.
John Dryden admired the Académie Française and greatly deplored that the English had "not so much as a tolerable dictionary, or a grammar; so that our language is in a manner barbarous" as compared with elegant French.
The PCI of scFvMEL/rGel treatment was found to act in a synergistic manner (p<0.05) as compared to the expected sum of the individual treatments scFvMEL/rGel and PDT with R = 1.15, indicating that the tumor growth delay by PCI of scFvMEL/rGel was more that twice as long as expected by an additive effect.
Across all clinical and ethnic groups, there was a fairly even distribution of statements expressing satisfaction with the physician's manner and rapport as compared with dissatisfaction.
Irradiation-only and vehicle-plus-irradiation groups showed a marked increase in the percentage of apoptotic lymphocytes, while melatonin pretreatments in a dose-dependent manner reduced it as compared with the irradiation-only and vehicle-plus-irradiation groups in all time points.
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