Sentence examples for manner and enhanced from inspiring English sources

In contrast, rosiglitazone, a known PPARγ agonist, induced TG accumulation in a PPARγ-dependent manner and enhanced mitochondrial function.

The fully trimethylated TMC, from 0.25 mg/ml, decreased transepithelial electrical resistance (TER) in a reversible manner and enhanced the permeation of the macromolecule FITC dextran 4 kDa (FD4) 2–5 fold.

Phthalate esters also increased the expression of cyclin-dependent kinase inhibitor 1 (p21Cin1) in a p53-dependent manner and enhanced the transcriptional activity of p53.

Additionally, the induction of IL-12 expression after infection with type I strains did not involve Myd88 signaling, whereas this was clearly Myd88-dependent with type II strains.> The ME49 strain activated ERK1/2 and p38 MAPK in an Myd88-dependent manner and enhanced the expression of IL-12, which the RH strain failed to do [ 26].

Also, STB-HO increased G1 cell population in a time and concentration dependent manner and enhanced the expression of p21, p27, p53 as cyclin dependent kinase (CDK) inhibitors [ 32- 34], attenuated the expression of proliferating cell nuclear antigen (PCNA) and cyclin D1, implying G1 arrest leading to cell death by STB-HO in HCT116 cells.

These years, transformable drug delivery systems (DDSs), which hold the capability of changing formulation morphology and subsequent functionality at the desired disease site, have shown great promise in control of spatio-temporal drug delivery/release manner and enhanced treatment efficacy.

Project management teams are responsible for nurturing the materialization in a collaborative manner and enhancing the productivity of the pipelines.

Accrual accounting would also create political incentives for our leaders to address Social Security's difficulties in a timely manner, and enhance the quality of public debate over the relative merits of competing reform proposals.

We propose a model in which ChoRE- and CCAAT-associated factors, upon receiving signals from diverse physiological cues, induce dynamic changes at Txnip promoter in a synergistic manner and enhance Txnip expression.

Coactivators are factors that can interact with nuclear receptors in a ligand-dependent manner and enhance their transcriptional activity.

IGFBP-3 is pro-apoptotic in an IGF-dependent manner, as well as an IGF-independent manner, and enhances the p53 DNA damage response in vitro [ 8, 9].