Sentence examples for manner and caused from inspiring English sources

Pre- or co-treatment of CYNOM-K1 cells from cynomolgus monkey embryo skin with Tat-Y1068 increased the transduction efficiencies in a dose-dependent manner and caused p38 phosphorylation.

F7 induced apoptosis in concentration- and time-dependent manner and caused cell cycle arrest at S-phase.

Mutant CAG repeats gave rise to toxic small RNA (sCAG) in a Dicer-dependent manner and caused a downstream silencing effect in an Ago2-dependent manner [ 93].

This treatment reduced the immunoreactivity of these proteins in a time- and dose-dependent manner, and caused the gap junction and adherens junction to separate longitudinally from the cell-cell contact sites, indicating the structural interdependency of these two junctions.

In the present study, our results showed that shikonin significantly inhibited the growth of A431 cells in a concentration- and time-dependent manner, and caused cell cycle arrest by upregulation of p21 and p27, and downregulation of cyclins and cyclin-dependent kinases.

We also found a very interesting effect, which appears to result from the interaction between the parametric and external responses in a nonlinear manner and causes the primary response to lose stability.

Preliminary anti-cancer mechanistic investigation was performed in terms of the cell cycle arrest and cell apoptosis assays of compound 6l against HCT116 using flow cytometry, and the results suggested that compound 6l inhibited tumor proliferation through inducing early and late cellular apoptosis in a concentration-dependent manner and causing cell cycle arrest in the S-phase.

ATP released from cells then stimulates purinergic receptors in nearby cells in a paracrine manner and causes both intracellular calcium signaling and ATP release.

Steve Johnston (Royal Marsden Hospital, London, UK) highlighted how growth factor receptors can activate the ER in a ligand-independent manner and cause antiestrogen resistance (abstract MS3-4 [ 1]).

If you eat too much junk food, you risk putting on weight in an unhealthy manner and causing additional health problems.

His demands and his manner irked Churchill and Roosevelt and caused persistent tension.