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We use both genetic and nutritional manipulations to test whether changes in arginase metabolism promote fibrosis and increase pathology in mdx mice.
We performed three field manipulations to test the general hypothesis that overfishing and the subsequent alteration of coral reef trophic dynamics are a cause of coral epizootics.
In the present study, we use 3 different task difficulty manipulations to test both models of rostrocaudal hierarchy across the lateral frontal cortex.
Similarly, empirical studies of sociotechnical systems 'in the wild' are severely constrained by researchers' limited ability to introduce structural and/or dynamic experimental manipulations to test hypotheses concerning their impact on system performance and safety-related outcomes.
Moreover, the follow-up manipulations to test predictions from the results of the analyses (single-sided trials, free choice trials) demonstrate the success of the method and the depth of understanding of the role of these structures.
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It should also be possible to use an ecological manipulation to test this model.
The experiment presented in this paper intentionally exploits this manipulation to test the framework's predictions.
Each flower was randomly assigned to one of four hand-pollination treatments: (i) covered but without manipulation to test for spontaneous autogamy, (ii) emasculated to test for agamospermy, (iii) artificially self-pollinated and (iv) outcrossed or by induced xenogamy.
The first, the mutual manipulability account, understands constitutive relevance in terms of the experimental manipulations used to test interlevel relations.
For all of these reasons, temporary waters lend themselves to surveys and experimental manipulations designed to test hypotheses about biological adaptation, population regulation, evolutionary processes, community composition and structure, and ecosystem functioning.
The goal of this manipulation was to test the impact of such a delay, which may be required in the case of spinal cord-injured patients in order to allow their stabilization and precise diagnosis before any intervention.
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