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Debate around three-parent IVF was prominent in the United Kingdom, where researchers were leading the effort to test mitochondrial manipulation technologies in clinical trials.
This is the first report of in vivo RMCE via phiC31 integrase in the silkworm, and thus represents a key step toward establishing genome manipulation technologies in silkworms and other lepidopteran species.
A recently developed Flippase-induced intersectional GAL80/GAL4 repression method incorporates several gene manipulation technologies in Drosophila to enable such fine-scale dissection in neural tissues.
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The resolution of these issues is essential to bring pluripotent cell-based genetic manipulation technology in the rat to the level of efficiency achieved in the mouse.
In the past two decades, advances in gene manipulation technologies have been applied widely in different aspects of molecular research, and have been especially useful in the functional analysis of genes.
"Optical tweezers and beam manipulation technologies are increasingly found in undergraduate teaching laboratories.
Many of these discoveries have been made possible by advances in transgenic gene manipulation technologies that have provided increasingly fine-scale methods of dissecting morphogenetic processes (Venken and Bellen 2007; del Valle Rodriguez et al. 2012).
Among several single-molecule manipulation technologies, magnetic tweezers have many unique advantages in terms of instrumentation simplicity and stability, experimental throughput, easy temperature control and solution exchanging.
In order to increase ATP pool size, the culture medium composition was optimized in this study because gene manipulation technologies are not preferable for industrial food production.
Recent advancements in single-cell measurement and manipulation technologies allow multiscale and multiparametric measurement of molecular contents, thereby enabling observation of molecular events at single-cell level.
An explosion of DNA sequencing, synthesis, and manipulation technologies has driven the development of synthetic genetic programs of increasing complexity in living cells.
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