Summary: Manipulation of T cells can enhance current CLL xenograft models, expanding their utility for investigation of tumour biology and pre-clinical drug assessment.
In summary, manipulations of PI 4,5 P2 levels profoundly and specifically affect Dia localization in vivo, demonstrating the involvement of PI 4,5 P2 in Dia apical targeting.
In summary, manipulations that recapitulate the effects of nutrient restriction and reduced insulin signaling specifically in tracheal terminal cells show that these cells are important metabolic mediators.
However the World Press have commissioned a report entitled Integrity of the Image, which in its summary states :"Manipulation is seen as involving material changes to an image through the addition or subtraction of content", and goes on to add, "Adjustments (such as limited cropping, dodging and burning, toning, colour adjustment, conversion to greyscale) to photographs are accepted".
In summary, the manipulation of the circadian network limited to adults can affect the free-running period of locomotor activity.
Summary: The manipulation of signals that control embryonic patterning allows human pluripotent stem cells to be differentiated into endothelial subpopulations with distinct haematopoietic, angiogenic and cardiogenic potential.
As a summary, micro-nanorobotic manipulation is the essential technique for accuracy positioning and manipulation.
In summary, biomaterial-based manipulation of cell-matrix interactions represents an important target for improving contractile force generation in engineered skeletal muscle.
In summary, both neurochemical manipulations produced similar rostrocaudal gradients for generating positive and negative motivated behaviors, and at similar overall intensities, but with slightly different valence biases (glutamate = positive motivation bias; GABA = negative bias).
In summary, our data indicate that manipulation of dendritic cell activity with cAMP-elevating agents provides a therapeutic tool for the treatment of antigen-specific autoimmune disorders.
