Sentence examples for manipulation of pathways from inspiring English sources
The manipulation of pathways to make unnatural variants of natural compounds, a process often termed combinatorial biosynthesis, has been robustly successful in prokaryotic systems.
This suggests that attempts to extend lifespan through diet restriction or the manipulation of pathways mimicking this process will have complicated effects on a host's ability to fight infections.
Human diseases could be treated by selective manipulation of pathways involved in their pathogenesis.
The liquid environment of zebrafish larvae facilitates the temporal manipulation of pathways through the addition of drugs direct to the embryo media.
In SS, however, the role of fractalkine in the etiology and pathogenesis of the disease deserves to be studied further through direct manipulation of pathways involving fractalkine.
We are hereby making available to the community, not only an abstract data model for a possible large adoption, but also the basic tools that allow the manipulation of pathways in this format.
Manipulations of pathways involved in D2 autoreceptor desensitization had distinct actions on D2S and D2L receptor-dependent GIRK currents.
These results suggest that 2C-like cells can emerge by the manipulation of two pathways, one pathway involving H3K56ac, HDAC5, and BRD7, and an indirect pathway involving H2AK119ub, RNF2, and Gata2.
Genetic manipulations of pathway components that result in dampened IIS extend lifespan in worms, flies and mice, and ameliorate age-dependent functional decline (Tatar et al., 2003; Piper et al., 2008).
However, the fact that inhibition of one endocytic pathway can increase or decrease prion infection depending on the strain argues against the idea that manipulation of endocytic pathways simply increases prion transport for lysosomal degradation.
PathwayExplorer [ 2] maps gene expression data to pathways, displaying the data in heatmap format, but does not allow for manipulation of the pathway, or creation of new pathways.
