Sentence examples for manipulation of mice from inspiring English sources

In this review, we focus on the physiological and pathophysiological roles of KATP channels learned from genetic manipulation of mice and naturally occurring mutations in humans.

Modeling of astrocytomas by genetic manipulation of mice suggests that deregulation of the pathways that control gliogenesis during normal brain development, such as the differentiation of neural stem cells (NSCs) into astrocytes, might contribute to GBM formation.

Care and manipulation of mice were performed in accordance with national and European legislations on animal experimentation.

Care and manipulation of mice were performed in accordance with European legislations on animal experimentation and approved by the Italian Ministry of Health.

Gene silencing and genetic manipulation of mice has allowed us to pinpoint AKAP150 as a positive intermediary of nutrient-mediated insulin secretion from pancreatic islets.

Care and manipulation of mice were performed in accordance with national and European legislations on animal experimentation, and approved by the institutional ethical committee.

We review recent advances in the use of UBM and high-frequency ultrasound Doppler for analyzing the developing mouse cardiovascular system, and the application of in utero UBM image-guided injections for direct manipulation of mouse embryos.

Genetic manipulation of mouse Tfap2a results in multiple defects in development and function of the skull and face (Brewer and Williams, 2004; Nelson and Williams, 2004; Nottoli et al., 1998; Pontoriero et al., 2008; Schorle et al., 1996; Zhang et al., 1996).

Despite these differences, the success of using human XIST transgenes to recapitulate XCI in the mouse [ 11, 12], and the recent demonstration that escape from XCI of human genes is possible from the mouse X chromosome [ 13], have illustrated the importance of manipulation of mouse models for understanding human XCI.

The results presented in this study strongly support the hypothesis that mouse S100A7 is the murine ortholog of human psoriasin/S100A7, and provide a rationale for the manipulation of mouse S100A7/psoriasin in mice to gain important insights into the function of human psoriasin/S100A7.

All housing and manipulations of mice followed an approved IACUC protocol AN-18677).