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The platform supports manipulation of matrix mechanics, curvature, and biochemical composition to mimic in vivo microenvironments.
Manipulation of matrix viscosity and compatibilization resulted in composites with good mechanical properties, and low percolation thresholds.
Examples include the manipulation of matrix cross-linking by modulating LOX expression and/or activity (Erler et al., 2006; Erler et al., 2009; Levental et al., 2009), or influencing ECM degradation by knocking out MMPs or by manipulating TIMP expression or activity (Sternlicht and Werb, 2001; Egeblad and Werb, 2002).
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However, for forests in a plantation matrix, the management of dispersal processes by manipulation of the matrix may be as important to conserving species and communities as is minimising extinctions.
Manipulation of the matrix properties, such as elasticity and geometry, in concert with ECM proteins will permit the investigation of multiple and distinct MSC environments.
Therefore, minimal manipulation of the matrix and the best conservation of the analytes of interest are desirable.
In summary, biomaterial-based manipulation of cell-matrix interactions represents an important target for improving contractile force generation in engineered skeletal muscle.
This algorithm can be used to derive the PMF f(c) for a specified location map of dense population of nodes in a MANET since the manipulation of large matrices is becoming practical with advances in high performance computing.
Cardiac tissue engineering requires finely-tuned manipulation of the extracellular matrix (ECM) microenvironment to optimize internal myocardial organization.
Moreover, manipulation of various data matrix properties affects tree topology in an unpredictable fashion, suggesting that complete coding regions of the plastome do not provide sufficient character information to resolve this rapid, ancient radiation.
By means of matrix manipulation and Fourier component analysis, the three-dimensional (3-D) governing equations of elastodynamics are converted into a system of ordinary differential equations with variable coefficients in the frequency and wavenumber domain.
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